Which gene did you mean? by Barend Mons.
Abstract:
Computational Biology needs computer-readable information records. Increasingly, meta-analysed and pre-digested information is being used in the follow up of high throughput experiments and other investigations that yield massive data sets. Semantic enrichment of plain text is crucial for computer aided analysis. In general people will think about semantic tagging as just another form of text mining, and that term has quite a negative connotation in the minds of some biologists who have been disappointed by classical approaches of text mining. Efforts so far have tried to develop tools and technologies that retrospectively extract the correct information from text, which is usually full of ambiguities. Although remarkable results have been obtained in experimental circumstances, the wide spread use of information mining tools is lagging behind earlier expectations. This commentary proposes to make semantic tagging an integral process to electronic publishing.
From within the post:
If all words had only one possible meaning, computers would be perfectly able to analyse texts. In reality however, words, terms and phrases in text are highly ambiguous. Knowledgeable people have few problems with these ambiguities when they read, because they use context to disambiguate ‘on the fly’. Even when fed a lot of semantically sound background information, however, computers currently lag far behind humans in their ability to interpret natural language. Therefore, proper semantic tagging of concepts in texts is crucial to make Computational Biology truly viable. Electronic Publishing has so far only scratched the surface of what is needed.
Open Access publication shows great potential, andis essential for effective information mining, but it will not achieve its full potential if information continues to be buried in plain text. Having true semantic mark up combined with open access for mining is an urgent need to make possible a computational approach to life sciences.
Creating semantically enriched content as part and parcel of the publication process should be a winning strategy.
First, for current data, estimates of what others will be searching for should not be hard to find out. That will help focus tagging on the material users are seeking. Second, a current and growing base of enriched material will help answer questions about the return on enriching material.
Other suggestions for BMC Bioinformatics?