neomodel by Robin Edwards.
From the webpage:
A high level wrapper around py2neo, providing a formal definition for your data model.
- Structured node definitions with type checking
- Lazy category node creation
- Automatic indexing
- Relationship traversal
- Soft cardinality restrictions
Supports: neo4j 1.8+, python 2.6, 2.7
If you are exploring graph land with Neo4j, you are likely to find this useful.