Inside the Variation Toolkit: Tools for Gene Ontology by Pierre Lindenbaum.
From the post:
GeneOntologyDbManager is a C++ tool that is part of my experimental Variation Toolkit.
This program is a set of tools for GeneOntology, it is based on the sqlite3 library.
Pierre walks through building and using his GeneOntologyDbManager.
Rather appropriate to mention an area (bioinformatics) that is exploding with information on the same day as GPU and database posts. Plus I am sure you will find the Gene Ontology useful for topic map purposes.