Another Word For It Patrick Durusau on Topic Maps and Semantic Diversity

October 23, 2010

An Algorithm to Find All Identical Motifs in Multiple Biological Sequences

Filed under: Bioinformatics,Biomedical,Pattern Recognition,Subject Identity — Patrick Durusau @ 5:25 am

An Algorithm to Find All Identical Motifs in Multiple Biological Sequences Authors: Ashish Kishor Bindal, R. Sabarinathan, J. Sridhar, D. Sherlin, K. Sekar Keywords: Sequence motifs, nucleotide and protein sequences, identical motifs, dynamic programming, direct repeat and phylogenetic relationships

Sequence motifs are of greater biological importance in nucleotide and protein sequences. The conserved occurrence of identical motifs represents the functional significance and helps to classify the biological sequences. In this paper, a new algorithm is proposed to find all identical motifs in multiple nucleotide or protein sequences. The proposed algorithm uses the concept of dynamic programming. The application of this algorithm includes the identification of (a) conserved identical sequence motifs and (b) identical or direct repeat sequence motifs across multiple biological sequences (nucleotide or protein sequences). Further, the proposed algorithm facilitates the analysis of comparative internal sequence repeats for the evolutionary studies which helps to derive the phylogenetic relationships from the distribution of repeats.

Good illustration that subject identification, here sequence motifs in nucleotide and protein sequences, varies by domain.

Subject matching in this type of data on the basis of assigned URL identifiers for sequence motifs would be silly.

But that’s the question isn’t it? What is the appropriate basis for subject matching in a particular domain?

Questions:

  1. Identify and describe one (1) domain where URL matching for subjects would be unnecessary overhead. (3 pages, no citations)
  2. Identify and describe one (1) domain where URL matching for subjects would be useful. (3 pages, no citations)
  3. What are the advantages of URLs as a lingua franca? (3 pages, no citations)
  4. What are the disadvantages of URLs as a lingua franca? (3 pages, no citations)

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BTW, when you see “no citations” that does not mean you should not be reading the relevant literature. What is means is that I want your analysis of the issues and not your channeling of the latest literature.

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