Another Word For It Patrick Durusau on Topic Maps and Semantic Diversity

January 12, 2013

Manual Alignment of Anatomy Ontologies

Filed under: Alignment,Bioinformatics,Biomedical,Ontology — Patrick Durusau @ 7:00 pm

Matching arthropod anatomy ontologies to the Hymenoptera Anatomy Ontology: results from a manual alignment by Matthew A. Bertone, István Mikó, Matthew J. Yoder, Katja C. Seltmann, James P. Balhoff, and Andrew R. Deans. (Database (2013) 2013 : bas057 doi: 10.1093/database/bas057)

Abstract:

Matching is an important step for increasing interoperability between heterogeneous ontologies. Here, we present alignments we produced as domain experts, using a manual mapping process, between the Hymenoptera Anatomy Ontology and other existing arthropod anatomy ontologies (representing spiders, ticks, mosquitoes and Drosophila melanogaster). The resulting alignments contain from 43 to 368 mappings (correspondences), all derived from domain-expert input. Despite the many pairwise correspondences, only 11 correspondences were found in common between all ontologies, suggesting either major intrinsic differences between each ontology or gaps in representing each group’s anatomy. Furthermore, we compare our findings with putative correspondences from Bioportal (derived from LOOM software) and summarize the results in a total evidence alignment. We briefly discuss characteristics of the ontologies and issues with the matching process.

Database URL: http://purl.obolibrary.org/obo/hao/2012-07-18/arthropod-mappings.obo.

A great example of the difficulty of matching across ontologies, particularly when the granularity or subjects of ontologies vary.

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